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The wheel is new build-package for python, intend to replace egg, more details here.
It is great to avoid compile from source code, easy and faster than egg.
This is example for pyzmq, it is nightmare if install on window msys if need to compile from source.
1) download right platform and python vesion for wheel file from phthonwheels.com if in Green list
2) $ pip install pyzmq-15.4.0-cp34-cp34m-win32.whl